. 2011 Sep 9;89(3):432–437. doi: 10.1016/j.ajhg.2011.07.022

Table 2.

Numbers of Candidate Genes Highlighted by Exome Sequencing

Any x of five individuals	1	2	3	4	5
Genes with homozygous or compound-heterozygous nonsynonymous, splice-site, or insertion/deletion variants	6721	5141	4030	3108	2162

With an estimated frequency < 0.01	80	5	1	0	0