Table 2.
All cause standardised mortality ratios (SMRs) at 20 years’ duration of diabetes in early onset type 1 diabetes cohort (0-14 years) and late onset type 1 diabetes cohort (15-29 years) diagnosed between 1970 and 1989
| Diagnosis subgroup | Follow-up range (period) | Follow-up range (years) | Age range (years) | Mortality/100 000 | Observed No of deaths | Person years | Expected No of deaths | SMR (95% CI) | Risk ratio* | P value for risk ratio |
|---|---|---|---|---|---|---|---|---|---|---|
| Early onset† | ||||||||||
| 1970-4 | 1970-94 | 0-20 | 0-34 | 240 | 68 | 28 346 | 19.6 | 3.5 (2.7 to 4.4) | 1.00 | – |
| 1975-9 | 1975-99 | 0-20 | 0-34 | 216 | 64 | 29 696 | 18.9 | 3.4 (2.6 to 4.3) | 0.81 | NS |
| 1980-4 | 1979-2004 | 0-20 | 0-34 | 176 | 57 | 32 373 | 18.7 | 3.0 (2.3 to 3.9) | 0.64 | 0.02 |
| 1985-9 | 1985-07 | 0-20 | 0-34 | 99 | 19 | 19 219 | 10.1 | 1.9 (1.2 to 2.9) | 0.36 | <0.003 |
| Late onset† | ||||||||||
| 1970-4 | 1970-94 | 0-20 | 15-49 | 223 | 49 | 21 924 | 35.1 | 1.4 (1.0 to 1.8) | 1.00 | – |
| 1975-9 | 1975-99 | 0-20 | 15-49 | 296 | 68 | 22 961 | 37.4 | 1.8 (1.4 to 2.3) | 1.32 | NS |
| 1980-4 | 1979-2004 | 0-20 | 15-49 | 330 | 71 | 21 546 | 31.8 | 2.2 (1.8 to 2.8) | 1.68 | 0.006 |
| 1985-9 | 1985-2007 | 0-20 | 15-49 | 408 | 57 | 13 966 | 19.8 | 2.9 (2.2 to 3.7) | 2.23 | <0.001 |
NS=not significant.
*Adjusted for age at diagnosis and duration of diabetes.
†P value for trend <0.001.