Table 1.
Results of the meta-analysis at the genus levela
| Genus level | Phoenix |
Vitek 2 |
P between systems (z-value) | ||||
|---|---|---|---|---|---|---|---|
| No. of isolates (no. of studies) | Correct identification rate (95% CI) | P within system (z-value) | No. of isolates (no. of studies) | Correct identification rate (95% CI) | P within system (z-value) | ||
| Overall analysis | 4,763 (21) | 97.70 (96.22-98.81) | 3,423 (15) | 97.59 (95.76-98.92) | 0.919 (0.102) | ||
| Comparator method | 0.013 (2.481) | 0.115 (1.576) | |||||
| Molecular | 387 (7) | 94.56 (90.82-97.39) | 543 (6) | 94.34 (85.31-99.25) | 0.954 (0.058) | ||
| Conventional | 4,376 (14) | 98.44 (97.04-99.40) | 2,880 (9) | 98.71 (97.79-99.39) | 0.704 (0.380) | ||
| Gram stain | 0.258 (1.131) | 0.518 (0.647) | |||||
| Positive | 2,626 (15) | 98.32 (96.96-99.30) | 1,523 (8) | 98.22 (95.48-99.72) | 0.933 (0.084) | ||
| Negative | 2,588 (11) | 97.13 (95.10-98.64) | 1,900 (8) | 97.16 (94.37-99.04) | 0.982 (0.022) | ||
| Subanalysis on Gram-positive bacteria | |||||||
| Comparator method | 0.024 (2.260) | 0.663 (0.436) | |||||
| Molecular | 193 (4) | 95.52 (91.83-98.13) | 330 (3) | 97.16 (84.09-99.48) | 0.733 (0.341) | ||
| Conventional | 2,433 (11) | 98.81 (97.55-99.63) | 1,193 (5) | 98.72 (96.61-99.83) | 0.365 (0.907) | ||
| Staphylococcus spp. | 0.053 (1.932) | 0.498 (0.677) | |||||
| Staphylococcus aureus | 791 (9) | 99.78 (99.33-99.98) | 69 (3) | 99.09 (95.56-99.96) | 0.435 (0.780) | ||
| Coagulase-negative staphylococci | 670 (8) | 98.70 (97.03-99.70) | 372 (4) | 99.74 (98.96-99.99) | 0.113 (1.587) | ||
| Enterococcus spp. | 526 (8) | 98.27 (95.39-99.78) | 239 (3) | 99.70 (98.61-99.99) | 0.153 (1.430) | ||
| Streptococcus spp. | 778 (7) | 96.70 (94.83-98.14) | 841 (5) | 96.10 (91.39-99.01) | 0.774 (0.287) | ||
| Subanalysis on Gram-negative bacteria | |||||||
| Comparator method | 0.077 (1.769) | 0.050 (1.957) | |||||
| Molecular | 192 (3) | 92.40 (83.24-98.14) | 213 (3) | 90.30 (74.85-98.84) | 0.771 (0.291) | ||
| Conventional | 2,396 (8) | 98.02 (96.16-99.27) | 1,687 (5) | 98.91 (97.95-99.56) | 0.293 (1.051) | ||
| Glucose fermentation | 0.811 (0.239) | 0.004 (2.898) | |||||
| Fermenters | 1,907 (9) | 97.62 (95.56-99.05) | 1,028 (4) | 99.60 (99.12-99.89) | 0.006 (2.765) | ||
| Nonfermenters | 353 (7) | 97.93 (95.70-99.36) | 872 (7) | 95.90 (91.61-98.71) | 0.292 (1.055) | ||
| Subanalysis on direct comparison studies | 480 (3) | 97.31 (95.68-98.56) | 480 (3) | 98.11 (94.90-99.77) | 0.598 (0.527) | ||
a
CI, confidence interval.