Fig. 2.
Visual predictive check of the final model. The open circles indicate the observations. The upper dotted line represents the 95th percentile of the observation. The continuous line represents the median of the observations. The lower dotted line represents the 5th percentile of the observations. The shaded areas are the simulated confidence intervals for the corresponding percentiles. For a clearer picture of the low concentrations, a log-transformed visual predictive check of the same model is shown on the right. The VPC is truncated at the LLOQ for both predictions and observations.