FIGURE 1.
Secretion of IL-6 from human macrophages is enhanced in response to lipid loading. Human Ctrl and ABCA1 KD THP-1 macrophages were cholesterol-loaded or not with acLDL for 24 h in serum-free media, and the secretion of IL-6 cytokine in the culture media was quantified on a semiautomated Biochip Array analyzer (Randox). *, p < 0.01; **, p < 0.001 versus unloaded Ctrl cells (None). #, p < 0.01; ##, p < 0.001 versus unloaded ABCA1 KD cells; †, p < 0.001 versus cholesterol-loaded Ctrl cells. Values are the means ± S.E. of three independent experiments performed in triplicate.