Table 1.
Scoring criteria for blinded examination of H&E-stained sections from the cecum
| Score | Neutrophil infiltrationa | Infiltration by mononuclear cellsa | Submucosal edema | Epithelial damage | Exudate |
|---|---|---|---|---|---|
| 0 | No changes (0–5) | No changes (0–5) | No changes | No changes | No changes |
| 1 | 6–20 | 5–10 | Detectable (<10%) | Desquamation | Slight accumulation |
| 2 | 21–60 | 10–20 | Mild (10–20%) | Mild erosion and mild loss of goblet cells/undifferentiated enterocyte hyperplasia | Mild accumulation |
| 3 | 61–100 | 20–40 | Moderate (20–40%) | Marked erosion and moderate loss of goblet cells/undifferentiated enterocyte hyperplasia | Moderate accumulation |
| 4 | >100 | >40 | Marked (>40%) | Ulceration and marked loss of goblet cells/undifferentiated enterocyte hyperplasia | Marked accumulation |
a
Numbers in parentheses indicate the numbers of cells per high-power field (magnification, ×400).