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. Author manuscript; available in PMC: 2011 Jul 18.
Published in final edited form as: J Invest Dermatol. 2009 Aug 27;130(2):398–404. doi: 10.1038/jid.2009.259

Figure 2. BMP signalling results in activation of the BMP-SMAD, but not BMP-MAPK pathways in human keratinocytes and fibroblasts.

Figure 2

Epidermal keratinocytes (A) and dermal fibroblasts (B) were treated with 50 ng/ml recombinant BMP-4 or vehicle control, the cell lysates were prepared at different time-points and analysed by immuno-blotting using antibodies against phospho-Smad1/5/8, phospho-p38 MAPK, phospho ERK1/2, and phosphor-JNK. Representative examples of three to four experiments are shown.