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. Author manuscript; available in PMC: 2012 Jul 15.
Published in final edited form as: J Immunol. 2011 Jun 20;187(2):861–869. doi: 10.4049/jimmunol.1004009

Figure 3. SFZ70.Rag1−/− mice contain peripheral CD4+ and CD8+ T cells and Helios+ Treg cells.

Figure 3

(A) Expression of CD4 and CD8 by TCRβ+ lymphocytes isolated from the skin-draining lymph nodes (LN), mesenteric lymph node (MLN) and spleens of SFZ70.Rag1−/−, OT-II.Rag1−/− or WT mice. Graphs show corresponding absolute numbers of CD4+ lymphocytes. (B) Expression of Foxp3 and CD25 (top) or Foxp3 and Helios (bottom) by CD4+ lymphocytes isolated from SFZ70.Rag1−/−, OT-II.Rag1−/− or WT mice. Statistical significance was determined using a one-way repeated-measures analysis of variance. A Tukey post-test was used to obtain the p-value for the bracketed pairwise comparisons. *, P < 0.05; **, P < 0.01; ***, P < 0.001. Data are representative of two experiments with 3–9 mice per group.