Fig. 6.
RORαsg/sg mice are protected against HFD-induced insulin resistance and glucose intolerance. A, B: glucose tolerance test (WT, n = 6; RORαsg/sg, n = 6) and insulin tolerance test (WT, n = 8; RORαsg/sg, n = 6) were performed in WT(HFD) and RORαsg/sg(HFD) mice. Glucose levels were analyzed every 20 min for up to 2–2.5 h. C: blood insulin levels were analyzed in WT(HFD) and RORαsg/sg(HFD) female mice (WT, n = 5; RORαsg/sg, n = 8). Data represent means ± SE. *P < 0.05, **P < 0.01, ***P < 0.001.
