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HFD induces steatosis. Representative hematoxylin/eosin-stained liver sections from mice fed control (A) or HFD (B–D) for 16 weeks. Increased lipid droplets are present within hepatocytes of the HFD mice compared with the control mice. Note the presence of multiple ballooned hepatocytes (solid arrow) and Mallory body (dashed arrow) in the liver from the HFD mice. Magnification: 10 × for panels A and B, 20 × for panel C, and 40 × for panel D.
