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. Author manuscript; available in PMC: 2011 Jun 15.
Published in final edited form as: Biol Psychiatry. 2002 Dec 15;52(12):1121–1133. doi: 10.1016/s0006-3223(02)01439-7

Table 1.

Characteristics of Subjects

Age/gender/race PMI TF pH Cause of death Medicationa Toxicology History of depression Family history
Control
1 71/M/C 24.0 5 6.82 N None known NDD None Alcohol abuse
2 58/M/C 21.5 5 6.78 N digoxin NDD None Alcohol and drug abuse
3 24/M/AAm 15.0 24 6.84 H None known NDD None None
4 30/F/C 9.0 29 6.75 N None known NDD None None
5 47/M/C 17.0 7 6.89 N famotidine NDD None Alcohol abuse
6 23/F/C 11.0 23 6.85 A levonorgestrel implant NDD None None
7 46/F/C 24.0 25.5 6.32 H maxitrol NDD None None
8 57/M/C 10.0 12 6.65 N naprosyn NDD None None
9 33/M/C 27.0 15 6.70 N None known cannabinoids None None
10 27/F/C 15.0 21 7.01 N captopril, ENDURONYL, ENALAPRIL, TOPRAL, lopressor NDD None None
11 60/F/AAm 19.0 11 6.74 N None known NDD None None
12 69/M/C 18.0 49 6.70 N None known NDD None None
13 60/M/AAm 27.0 45.7 6.75 H None known NDD None None
14 51/M/C 28.0 24.5 6.64 N None known NDD None None
15 52/M/C 17.0 45.9 6.28 N None known NDD None None
16 53/M/AAm 23.0 45.2 6.77 E None known NDD None None
17 18/F/C 27.0 43.4 6.78 A None known NDD None None
18 39/M/C 21.0 13.9 6.74 N None known lidocaine None None
19 59/M/C 6.0 42.5 6.79 N None known lidocaine None None
20 38/M/C 30.0 42.3 6.74 N None known NDD None None
21 42/M/C 20.0 11.9 6.82 N None known NDD None None
Average 45.6 20.0 25.8 6.73
Age/gender/race PMI TF pH Cause of death Medicationa Toxicology History of depression Family history Duration of alcoholismb Age of onset
Alcohol
22 50/M/C 17.0 34 6.67 S TRAZODONE-NON COMPLIANT EtOH 0.12 MDD Father: Alcohol abuse 2 48
23 61/M/AAm 27.0 30 6.68 N NITROGLYCERIN NDD No Father and brothers: Alcohol abuse 46 15
24 36/M/C 15.0 13 6.72 S AMITRIP, chlordiazepoxide, metronidazole, buspirone EtOH 0.19, amitrip, diazepam, cocaine metabolite MDD Alcohol abuse, suicide attempts, affective disorders 21 15
25 48/F/C 30.0 18 6.23 A IMIPRAMINE, PAROXETINE, VALPROATE, CLONAZEPAM, LUVOX? imipramine, acetone, isopropanol, lidocaine Moderate BPD, recently depressed Father: Alcohol abuse, Maternal grandmother: bipolar depression 33 15
26 29/M/C 27.0 24 6.75 N None known NDD Depressed mood, several episodes in last year Father: attempted suicide, Alcoholic uncle 14 15
27 37/M/C 19.0 16 6.89 S SERTRALINE 1DAY, Hx: paroxetine EtOH 0.13 moderate MDD Both parents alcoholic 23 14
28 30/M/C 12.0 18 6.49 A None known EtOH 0.17, CO 49% No Father and brother: Alcohol abuse 15 14
29 54/M/C 24.0 12 6.42 N None known lidocaine No Sister: heavy drinker 39 15
30 41/F/C 24.0 11 6.74 N None known diazepam, chlorpheniramine, lidocaine No Alcohol abuse 20 21
31 51/M/C 22.0 9 7.07 S SERTRALINE EtOH 0.16 Depressed mood, long periods Alcohol abuse 33 18
32 59/M/C 36.0 37.5 6.74 S None known EtOH 0.08 No None 39 20
33 46/M/C 26.0 35.1 6.84 N None known NDD No Father, grandfather: Alcoholic 34 12
34 50/M/C 14.0 30.1 6.66 A GLUXOTROL, ISOSORBIDE, BUMETANIDE, DILTIAZEM, FOSINOPRIL EtOH 0.27 No Aunt: depression, suicide attempt. Brothers (3): emotional, alcohol, drug problems 20 30
35 44/M/C 17.0 28.8 6.87 N None EtOH 0.12 No Not reported 26 18
36 40/F/C 27.5 15.7 6.67 N ALBUTEROL NDD No Sister: emotional problems 21 19
37 44/M/C 20.0 13.7 6.77 S FLUOXETINE, LORAZEPAM, diclofenac fluoxetine MDD, mild Father: alcoholic, Aunt: depression 10 34
38 30/F/C 17.0 13 6.77 S fluoxetine, sertraline, alprazolam, paroxetine, BUPROPRION EtOH 0.26 MDD, single moderate Aunts and uncles with alcohol problems 9 21
Average 44.2 21.9 21.11 6.70

AAm, African American; A, accident; BPD, bipolar disorder; C, caucasian; E, electrocution; F, female; H, homicide; M, male; MDD, major depressive disorder; N, natural; NDD, no drugs detected; PMI, postmortem interval (hours), defined as the time between death and the beginning of the formalin-fixation; S, suicide, TF, time in formalin (months); EtOH, ethanol blood level; Amitrip, Amitriptyline.

a

Capitalized drugs were prescribed in last month of life.

b

The duration (years) of alcohol dependence covers the time between the first display (and not necessarily diagnosis) of signs of dependence and the date of death.