Figure 4.
Summary of interneuron responses to 8-OH-DPAT and saline microinjections. Distribution of percentage changes in firing rate (controlled for speed of movement) after saline (top) or 8-OH-DPAT (bottom) microinjection. Thin, solid bars at the top of each graph indicate the mean of the distribution. Broken bars indicate ± 1s.d.. Broken bars crossing both graphs depict ±2 s.d. of the postsaline distribution. After 8-OH-DPAT microinjections, the distribution of interneuron responses is flattened relative to the saline distribution indicating the diversity of interneuron responses to the drug treatment. The variance of the two distributions was found to be significantly different using Fisher’s test for homogeneity of variance (F ratio 7.36, P < 0.05, df 47, 19).