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A, MSCs showed typical spindle-shaped morphology. Scale bar 100 µm. B, FACS analysis showed that 99% of these MSCs expressed CD44 and CD29, but not c-kit, CD31, and CD34. C, Chromosome analyses of normal MSCs showed normal karyotype, 40 XY. D Chromosome analyses of tumor-forming MSCs demonstrated multiple chromosomal abnormalities including fusion, fragmentation, and ring formation.
