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. Author manuscript; available in PMC: 2011 Jun 1.

Published in final edited form as: Nature. 2010 Jun 27;466(7303):267–271. doi: 10.1038/nature09145

Fig 2 — NF-κB response characteristics at different TNF-α doses. Error bars indicate the standard deviation from the median response time, and are indicative of the natural variation in single cell response. A Peak nuclear p65/dsRed localization intensity vs. TNF-α concentration. The median peak intensity (red squares) changes by only a factor of four with in response to four orders of magnitude change in TNF-α concentration. B The integrated area under the first peak vs. TNF concentration for a single experiment, showing that the total NF-κB nuclear activity in the first peak remains constant. C Response time vs. TNF-α concentration. The cells activate faster for higher concentrations. D Number of nuclear localization oscillations vs. TNF-α concentration.

Fig 2 — NF-κB response characteristics at different TNF-α doses. Error bars indicate the standard deviation from the median response time, and are indicative of the natural variation in single cell response. A Peak nuclear p65/dsRed localization intensity vs. TNF-α concentration. The median peak intensity (red squares) changes by only a factor of four with in response to four orders of magnitude change in TNF-α concentration. B The integrated area under the first peak vs. TNF concentration for a single experiment, showing that the total NF-κB nuclear activity in the first peak remains constant. C Response time vs. TNF-α concentration. The cells activate faster for higher concentrations. D Number of nuclear localization oscillations vs. TNF-α concentration.