TABLE 2.
MRI Features in Neonates With AIS and Without and With Seizures After Hospital Discharge
| Feature | Total (N = 46) | Without Seizures (n = 35) | With Seizures (n = 11) | Pd |
|---|---|---|---|---|
| AIS location,an (%) | ||||
| Unilateral anterior cerebral artery | 0 (0) | 0 (0) | 0 (0) | — |
| Unilateral MCA | 23 (50) | 17 (49) | 6 (55) | .50 |
| Unilateral posterior cerebral artery | 1 (2) | 1 (3) | 0 (0) | .76 |
| Multiple territories | 22 (48) | 17 (49) | 5 (45) | .56 |
| Bilateral MCA only | 7 (15) | 4 (11) | 3 (27) | .21 |
| MCA + other | 14 (30) | 12 (34) | 2 (18) | |
| Multiple territories without MCA | 1 (2) | 1 (3) | 0 (0) | .27 |
| Bilateral involvement,an (%) | 17 (37) | 12 (34) | 6 (55) | .20 |
| Stroke size according to modASPECT score, mean (SD)b,c | 7.7 (4.7) | 6.7 (3.9) | 11 (5.8) | .01 |
| Hemorrhage,bn (%) | ||||
| None | 29 (72.5) | 24 (77) | 5 (56) | .22 |
| Punctate | 7 (17.5) | 4 (13) | 3 (33) | .32 |
| Confluent | 4 (10) | 3 (10) | 1 (11) | 1.0 |
| Additional white matter disease,bn (%) | 8 (20) | 7 (23) | 1 (11) | .65 |
| Additional arterial watershed injury,bn (%) | 12 (30) | 5 (16) | 7 (78) | .10 |
a
Location as determined by changes on diffusion weighted imaging at the time of presentation.
b
Original images not available for further analysis in 6 patients.
c
See Methods for details on modified ASPECTS calculation.
d
P values for binomial variables calculated using Fisher's exact test; P value for comparison of mean stroke size calculated using Student's t test of independent variables.