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. 2004 Jan;48(1):15–22. doi: 10.1128/AAC.48.1.15-22.2004

TABLE 2.

MICs of β-lactams for K. pneumoniae 11978; K. pneumoniae CIP53153 harboring natural plasmid pA-1; E. coli DH10B harboring recombinant plasmids pVT-1, pVT-2, and pVT-3; E. coli DH10B harboring natural plasmid pA-1 alone or with pA-2; and E. coli DH10B and K. pneumoniae CIP53153 reference strains

β-Lactam(s)a MIC (μg/ml)
K. pneumoniae 11978 K. pneumoniae CIP53153 (pA-1) (OXA-48) K. pneumoniae CIP53153 E. coli DH10B (pA-1) (OXA-48) E. coli DH10B (pA-1, pA-2) (TEM-1, SHV-2a, OXA-47, OXA-48) E. coli DH10B (pVT-1) (OXA-48) E. coli DH10B (pVT-2) (OXA-47) E. coli DH10B (pVT-3) (SHV-2a) E. coli DH10B
Amoxicillin >512 >512 >512 >512 >512 >512 >512 >512 4
Amoxicillin + CLA >512 128 4 >512 >512 >512 128 128 4
Ticarcillin >512 >512 >512 >512 >512 >512 >512 >512 4
Ticarcillin + CLA >512 128 2 >512 >512 >512 128 256 4
Piperacillin >512 8 2 64 256 128 32 >512 2
Piperacillin + TZB 512 4 0.5 64 128 128 16 128 2
Cephalothin >512 0.5 0.5 8 512 64 2 >512 4
Cefuroxime 256 0.12 0.12 8 8 8 4 512 4
Cefoxitin 128 2 2 4 8 8 1 32 4
Ceftazidime 512 0.12 0.12 0.12 64 0.12 0.06 >512 0.06
Ceftazidime + CLA 256 0.12 0.12 0.12 2 0.12 0.06 2 0.06
Cefotaxime 64 0.06 0.06 0.25 2 0.25 0.06 128 0.06
Cefepime 32 0.06 0.06 0.25 0.25 0.06 0.06 32 0.06
Cefpirome 128 0.12 0.06 0.5 0.5 0.25 0.12 32 0.06
Moxalactam 64 0.06 0.06 4 4 2 0.06 1 0.06
Aztreonam 512 0.06 0.06 0.06 64 0.06 0.06 >512 0.12
Imipenem 64 2 0.06 2 2 2 0.06 0.25 0.06
Meropenem 64 0.25 0.06 0.25 0.25 0.25 0.06 0.06 0.06
a

CLA, clavulanic acid at a fixed concentration of 2 μg/ml; TZB, tazobactam at a fixed concentration of 4 μg/ml.