. 2011 Jan 19;31(5):1321–1333. doi: 10.1038/jcbfm.2010.234

Table 2. Summary of the effect size, cluster size, and MNI coordinates of brain locations where the highest (voxelwise-corrected P<0.05) increase in absolute CBF and significant differences in rCBF were observed.

Structure	t-value	No. of voxels 2 × 2 × 2 mm³	x	y	z
CBF_{Morphine (post−pre)}>CBF_{Placebo (post−pre)}
Cerebellum (IX, tonsil)	5.74	3041	50	36	19
Pregenual ACC	5.31	1534	52	78	45
Right frontal operculum	5.37	529	26	73	42
Left cerebellum crus	5.03	133	58	21	15
Right temporal pole	5.12	119	28	65	16
Brainstem, pons	4.96	159	47	51	30

CBF_{Alcohol (post−pre)}>CBF_{Placebo (post−pre)}
Left precentral	4.75	100	63	55	69
Left fusiform	4.89	75	69	51	22
Right hippocampus	4.74	72	30	42	36
Left premotor	4.94	52	57	62	70
Left cingulate cortex	4.70	50	52	52	60
Left occipital pole	4.82	45	61	15	35
Right premotor	4.60	36	39	63	67
Left prim. somatosensory	4.60	15	73	59	58

rCBF_{Morphine (post−pre)}>rCBF_{Alcohol (post−pre)}
Cerebellum	6.77	11473	29	25	11
ACC	4.53	582	47	83	39

rCBF_{Morphine (post−pre)}<rCBF_{Alcohol (post−pre)}
Left primary motor, somatosensory, and lateral occipital	5.07	2141	72	62	44
Left occipitotemporal	5.20	1257	67	32	37
Right hippocampus	5.99	1085	29	53	27
Left hippocampus	5.07	619	63	45	30
Left putamen	4.14	83	59	61	40
Left superior temporal	4.20	69	73	49	34
Right lateral occipital	4.02	62	22	31	48

ACC, anterior cingulate cortex; CBF, cerebral blood flow; MNI, Montreal Neurological Institute; rCBF, relative CBF.