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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Drug Metab Rev. 2010 Aug;42(3):446–471. doi: 10.3109/03602530903491881

Figure 2. Relationship between in vitro intrinsic Clbiliary values generated for compounds in rat and human SCH with in vivo Clbiliiary data.

Figure 2

Rat in vivo Clbiliary of 11 compounds vs. predicted in vitro Clbiliary data generated in rat SCH [blue; r2=0.99; (Liu et al., 1999a)] and human in vivo Clbiliary of three compounds vs. predicted in vitro Clbiliary data generated in human SCH [green; (Ghibellini et al., 2007)].