Skip to main content
. Author manuscript; available in PMC: 2011 May 16.
Published in final edited form as: Integr Biol (Camb). 2010 Dec 7;3(4):439–450. doi: 10.1039/c0ib00063a

Fig 4.

Fig 4

SHG signal intensity profiles around MCF-DCIS cell clusters. Two co-cultured clusters (co-A and co-B) show heterogeneous intensity profiles around clusters, while two mono-cultured clusters (mono-A and mono-B) show relatively homogeneous intensity profiles around clusters. Cluster outlines were found after F-actin staining of clusters. Collagen structures (green) were visualized by SHG signal and merged with F-actin-stained cells (red). Seven points were randomly selected around clusters, and lines (approximately 50 μm) were radially extended out to the surrounding collagen matrix from the points. Intensity profiles on the lines were measured. Scale bar represents 25 μm.