Table 3b.
ROC analysis and Wilcoxin rank-sum test - Chronic pancreatitis biomarker candidates.
| Marker candidate | Chronic pancreatitis cases vs non-disease control | Chronic pancreatitis cases vs all controls (non-disease control and cancer) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AUC | Sens at 100% Spec | Sens at 95% Spec | Sens at 90% Spec | Spec at 100% Sens | Spec at 95% Sens | Spec at 90% Sens | p value (Wilcoxin rank-sum test) | AUC | Sens at 100% Spec | Sens at 95% Spec | Sens at 90% Spec | Spec at 100% Sens | Spec at 95% Sens | Spec at 90% Sens | p value (Wilcoxin rank-sum test) | |
| AZGP1 | 0.88 | 56% | 56% | 78% | 0% | 0% | 70% | 0.0004 | 0.83 | 47% | 50% | 56% | 14% | 16% | 51% | <0.0001 |
| APOA2 | 0.65 | 50% | 50% | 50% | 0% | 0% | 0% | 0.1992 | 0.60 | 5% | 5% | 50% | 0% | 0% | 0% | 0.3079 |
| LTF | 0.73 | 39% | 39% | 39% | 14% | 14% | 57% | 0.0846 | 0.63 | 17% | 17% | 17% | 7% | 50% | 50% | 0.2032 |