Figure 3.
Panc-1 cells demonstrate co-localization of v-ATPase with cortactin, a component of the cellular invasion apparatus. Immunofluorescent (IF) images of the V1E isoform (a, red) and cortactin (b, green) in Panc-1 cells reveal that in those cells with plasma membrane v-ATPase localization proximity to known components of the cellular invasion apparatus such as cortactin was observed. Non-overlapping intracellular areas of V1E localization are shown (inset, red circular structures, arrowhead) adjacent to merged areas (c, inset, yellow).
