Fig. 10.
Comparisons of activity of putative medium-spiny neurons recorded during training on 2 versions of the T-maze task. A: previous task version, in which the instruction cues were presented from immediately before turn until goal reaching. B and C: average percent-correct performance (B) and run times (C) of rats trained on the advance-cueing version (n = 7, purple) and those trained on the midrun-cueing version (n = 7, aqua). Arrows indicate the stage at which rats reached the criterion in both tasks. Error bars indicate standard error of the mean. D: average raw activity of TRNs during overtraining (stages 5-9) on the advance-cueing task (purple) and the midrun-cueing task (aqua). Inset: activity of the advance-cueing version aligned at tone offset (purple) with activity of the midrun-cueing version aligned at the click to indicate the beginning of a trial (aqua). E: activity of NTRNs during overtraining on the two task versions, plotted as in D. F: P values for differences in average raw firing rates of TRNs between the advance-cueing and midrun-cueing tasks shown in D. G: slope of the regression fitted to changes in average firing rates of TRNs for each 10-ms bin over the course of training on the advance-cueing task (purple) and the midrun-cueing task (aqua), plotted with 95% confidence bounds. Significant increases and decreases with training are indicated by positive (above the red dotted line) and negative (below the red dotted line) regression slopes.