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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Nat Neurosci. 2011 Mar 20;14(4):437–441. doi: 10.1038/nn.2780

Figure 6. Activation of canonical Wnt/β-catenin signaling does not inhibit Schwann cell myelination.

Figure 6

(a) Electron microscopy of sciatic nerve cross-sections from control (Catnlox(ex3)) and Wnt/β-catenin activating mice in the Schwann cell lineage (Catnlox(ex3)/+;DhhCre/+) at P15. (b) The g-ratio (ratio of axon diameter/ myelinated fiber diameter) of the myelinated axons was measured in sciatic nerves of control and β-catenin activating mice. Histogram presented the percentage of counts for myelinated axons at the different range of g-ratio as mean ± s.d. Scale bar, 5 μm.