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Macroscopic observation and histopathology showing late colonic neoplasms developed in AOM/DSS-treated mice. Tubular adenoma (a, d); moderately differentiated adenocarcinoma (b, e); and moderately differentiated adenocarcinoma invading into the mucosa (c, f). Macroscopic analysis in necroscopy (a, b, c) and hematoxylin-eosin stain (d, e, f). Original magnification ×4. (Unpublished data).
