Figure 3.
Efficacy in ferrets of 1 dose of s-LAIV, 2 doses of s-TIV, or monovalent live attenuated 2009 pandemic H1N1 influenza vaccine against challenge with 106 TCID50 CA/7 wt virus. Virus titers were determined on days 1 and 5 after challenge; virus titers are expressed as log10TCID50/g of tissue. Horizontal bars represent mean titers from individual ferrets, and symbols represent titers from individual ferrets. The dotted lines represent the lower limit of detection. A, Level of replication in the upper respiratory tract after challenge. B, Level of replication in the lower respiratory tract after challenge.