FIG. 5.
CD40L-bearing virions promote mRNA expression of LTA, LTB, and AID. mRNA expression levels of LTA (A), LTB (B), and AID (C) were assessed by qRT-PCR in tonsillar B cells that were exposed for 8 or 24 h to the agents described in the legend of Fig. 3. Results are expressed as fold changes above the mock control and are normalized to 18S expression. The data shown are the means ± standard deviations for triplicate samples and are representative of two separate experiments performed with different donors. Asterisks denote statistically significant data (ANOVA test, Bonferroni-corrected P values; *, P < 0.05; **, P < 0.01).