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. 2001 Mar 13;98(6):3276–3281. doi: 10.1073/pnas.051584498

Figure 1.

Figure 1

Histological analysis of cardiac allografts. (a) Voerhoeff elastin stain of the rejected cardiac allograft from recipient no. 13511 on POD 5 (×100). Asterisk indicates internal elastic lamina. (b) Trichrome stain of the rejected cardiac allograft from recipient no. 13692 on POD 5 (×100). Blue staining indicates the presence of collagen within occluding neointima, as indicated by transparent arrow. (c) α-Actin staining of the rejected cardiac allograft from recipient no. 13692 on POD 5 showing smooth muscle cell accumulation within the intima, indicated by filled arrow (×100). (d) Voerhoff elastin stain of cardiac allograft from DRβInline graphic control pig no. 13914 at POD 15 showing no intimal thickening (×100). (e) Immunofluorescent staining for IgM on the rejected cardiac allograft from recipient no. 13692 on POD 5 showing antibody deposition along the arteriolar endothelium (×250). (f) Immunofluorescent staining for IgG on the rejected cardiac allograft from recipient no. 13692 on POD 5 showing antibody deposition along arteriolar endothelium (×250). Naïve control hearts did not stain for antibody.