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. 2011 Jan 31;286(13):11604–11615. doi: 10.1074/jbc.M110.198390

FIGURE 7.

FIGURE 7.

Regulation of IL-8 gene expression in CF cells. A model appropriately summarizes the proinflammatory status of CF cells due to increased expression of miR-155. The aberrant up-regulation of miR-155 leads to increased IL-8 levels via down-regulation of the expression of intermediate target gene of miR-155, SHIP1 (INPP5D).