Fig. 1.
Heatmap of log10-transformed proportions of microbial taxa found in the vaginal bacterial communities of 394 women of reproductive age (color key is indicated in the lower right corner). (A) Complete linkage clustering of samples based on the species composition and abundance of vaginal bacterial communities that define community groups I to V. (B) Nugent scores and pH measurements for each of the 394 community samples (color key is indicated above C). (C) Complete linkage clustering of taxa based on Spearman's correlation coefficient profiles, which were defined as the set of Spearman's correlation coefficients calculated between one taxon and all of the other taxa (SI Materials and Methods). (D) Spearman's correlation coefficients between the presence of a taxon and the Nugent score or pH of a sample. (E) Shannon diversity indices calculated for 394 vaginal communities (two singletons were excluded).