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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Mucosal Immunol. 2010 Oct 20;4(2):186–196. doi: 10.1038/mi.2010.70

Figure 3.

Figure 3

Frequencies of leukocyte subsets in CD11c-TL1A transgenic (tg) mice and activation status of CD4 + T cells. (a) Representative (n = 5) flow cytometric plots of spleen cells from tg or wild-type (wt) mice demonstrating similar frequencies of CD4 + T cells, CD8 + T cells, macrophages (CD11b +), dendritic cells (CD11c high), B cells (CD19 +), and natural killer (NK) cells (NK1.1 + CD3 −) in tg and wt mice. However, fewer invariant natural killer T (NKT) cells (NK1.1 + CD3 + or CD1d/α-galactosylceramide (αGalCer) tetramer +) were present in CD11c-TL1A tg mice. (b) Representative flow cytometric plots showing expression of activation/memory markers on peripheral CD4 + Foxp3 − cells from wt and tg mice (7–13-week-old mice; the data shown are representative of five mice per group).