Figure 7. Effect of Gαi2 genetic deletion on immune cell population following CLP.
Gαi2 (−/−) and WT mice were subjected to CLP and sham operation. Twenty-four hours after CLP, mice were sacrificed. The spleens were isolated and CD4+ cells (A), CD8+ cells (B), dendritic cells (C) were determined by Flow Cytometry analysis. The subsets of CD4+ T cells including Th1 cells (D), Th2 cells (E), Th17 cells (F) and T-reg cells (G) were analyzed. Data are representative of 4–5 independent experiments. *, p<0.05 compared to sham group; #, p<0.05 compared to WT CLP group; **, p<0.05 compared to Gαi2 (−/−) sham.
