Figure 5. Effect of Gαi2 genetic deletion on bacterial clearance following CLP.
Gαi2 (−/−) and WT mice were subjected to CLP and sham operation. Twenty-four hours after CLP, mice were sacrificed. Bacterial loads in peritoneal fluid (A), blood (B) and lung tissue (C) were determined by colony count. Data represent means ± SE from 5–6 animals. *, p<0.05 compared to sham group; #, p<0.05 compared to WT CLP group.
