Table 1.
Clinical outcome of oocyte freezing and thawing in patients with no sperm or insufficient number of sperm on the day of in vitro fertilization
|
Group 1 Frozen oocytes to be fertilized with autologous sperm of poor quality in severe azoospermia or oligoasthenoteratozoospermia |
Group 2 Frozen oocytes to be fertilized with autologous or donated sperm of normal quality |
TOTAL | |
|---|---|---|---|
| OOCYTE FREEZING | |||
| Patients | 9 | 13 | 22 |
| Mean female age (years) | 31.3 (range 28-36) | 31.9 (range 27-40) | 31.7 (range 27 - 40) |
| Female indications of infertility | 4 (44.4%) | 10 (76.9%) | 14 |
| Freezing cycles | 9 | 14 | 23 |
| Frozen metaphase II oocytes | 83 | 83 | 166 |
| Mean number of frozen oocytes per patient | 9.2 (min. 4-max. 14) | 6.4 (min. 4-max. 12) | 7.2 (min. 4 - max. 14) |
| OOCYTE THAWING | |||
| Patients | 9 | 13 | 22 |
| Thawing cycles | 10 | 13 | 23 |
| Thawed metaphase II oocytes | 83 | 83 | 166 |
| Thawed metaphase II oocytes per cycle | 8.3 (min. 4-max. 14) | 6.4 (min. 4-max. 12) | 7.2 (min. 4 - max. 14) |
| Thawed metaphase II oocytes per patient | 9.2 (min. 4-max.14) | 6.4 (min. 4-max. 12) | 7.5 (min. 4 - max. 14) |
| Survived oocytes | 56 (67.5%) | 61 (73.5%) | 117 (70.5%) |
| Fertilized oocytes after ICSI | 38 (40.9%) | 34 (55.7%) | 72 (61.5%) |
| Embryos | 23 | 34 | 57 |
| Blastocysts | 4 | 8 | 12 |
| Blastocyst rate | 17.4% | 23.5% | 21.0% |
| Embryo transfers (ET) | 5 | 7 | 12 |
| Double embryo transfers | 4 | 7 | 11 |
| Pregnancies | 1 | 3 | 4 |
| Clinical pregnancy rate per ET | 20.0% | 42.8% | 33.3% |
| Clinical pregnancy rate per thawing cycle | 11.1% | 23.1% | 17.4% |
| Birth of a child | 1 | 3 | 4 |
All differences between the two groups were not statistically significant.