Table 2.
Significant effects of word generation, task difficulty and group effects during the performance of a verbal fluency task by subjects with schizophrenia, bipolar disorder and healthy controls.
| Coordinates | |||||
|---|---|---|---|---|---|
| Brodmann area | x | y | z | Z max | |
| Word generation > repetition | |||||
| Inferior frontal gyrus | BA47 | -34 | 28 | 0 | 4.58 |
| BA45 | -50 | 28 | 16 | 3.89 | |
| BA44 | -52 | 12 | 24 | 5.44 | |
| Inferior frontal gyrus/insula | BA47 | 36 | 24 | 0 | 3.5 |
| Inferior frontal gyrus/orbital | BA47 | -50 | 36 | -8 | 2.95 |
| Superior temporal gyrus | BA 38 | -52 | 20 | -16 | 4.18 |
| Thalamus | -8 | -14 | 10 | 3.37 | |
| Word generation < repetition | |||||
| Precuneus | BA 7 | -2 | -68 | 48 | 4.8 |
| Ventral anterior cingulate | BA10/25 | 4 | 44 | -8 | 4.11 |
| Word generation with difficult > easy letters | |||||
| Dorsal anterior cingulate (rostral, supracallosal) | BA24/32 | -4 | 24 | 32 | 2.65 |
| Effect of diagnostic group | |||||
| Schiz. > bipolar > control | |||||
| Dorsal anterior cingulate (caudal, supracallosal) | BA24 | -2 | 0 | 40 | 3.12 |
| Middle frontal gyrus | BA46/44 | -40 | 32 | 40 | 3.81 |
| Putamen | 18 | 14 | -8 | 3.23 | |
| Schiz. > (bipolar, control) | |||||
| Inferior and middle frontal gyrus | BA44/9/6 | 44 | 12 | 40 | 4.29 |
| Superior frontal gyrus | BA9 | 18 | 52 | 32 | 3.18 |
| Inferior frontal gyrus | BA44/6 | 48 | 10 | 16 | 2.75 |
| (Schiz., bipolar) > control | |||||
| Precuneus | BA7 | -4 | -66 | 48 | 4.24 |
| Precuneus/Superior occipital cortex | BA7 | 18 | -82 | 48 | 4.12 |
| Angular/supramarginal gyrus | BA39/40 | 56 | -38 | 48 | 3.29 |
| Angular gyrus | BA39 | -42 | -58 | 48 | 2.72 |
| Posterior cingulated | BA23 | 0 | -30 | 32 | 2.83 |