TABLE 1.
Effect of intraperitoneal administration of thioridazine and AMD3100 upon CFU and WBC in mouse peripheral blood
Mean ± S.E. from three independent experiments performed on different days are shown (4 mice per treatment).
| Treatment | CFU/ml in peripheral blood | WBC count/ml × 106 |
|---|---|---|
| Vehicle | 68.1 ± 9.1 | 3.7 ± 0.6 |
| Thioridazine | 216.8 ± 42.1 | 3.0 ± 0.3 |
| AMD3100 | 511.8 ± 78.8a | 7.8 ± 0.7b |
a Means are significantly different (p < 0.05, according to one-way ANOVA).
b Statistically significant difference was found between vehicle and AMD3100 treatment (p < 0.05, according to unpaired t test). No significant difference was found between vehicle and thioridazine treatment for WBC count.