FIG. 1.
A: Teglicar-dependent suppression of glucose and ketone bodies production by hepatocytes isolated from 16-h-fasted rats and incubated in presence of 10:1 lactate/pyruvate and 1 mmol/L oleate. B: Relationship between hepatocytes glucose production and the concentration of pyruvate/lactate in Krebs medium containing 1 mmol/L oleate in the presence or absence of 10 μmol/L teglicar. Each point represents the mean ± SE from eight different hepatocyte preparations in triplicate: ***P < 0.001; **P < 0.01 vs. control (CTRL) + oleate.