Figure 8. Increased IGF-1R expression and phosphorylation of AKT in relapsed patient samples.
Paired tumor samples (pt 1, Table S5) taken before treatment (pre-treatment, sub-cutaneous back lesion) and drug resistant (post-relapse, small bowel) were analyzed for IGF-1R expression or phospho-AKT by immunohistochemistry. Low magnification representative images are shown on the left (scale bar, 500 μm) and higher magnification images are on shown on the right (scale bar, 50 μm). See also Figure S7 and Table S5.
