Figure 3. CB1 and CB2 receptor mediates inhibition of focal adhesions formation.

Confocal microscopic visualization of JWH-015 and Win55,212-2 pretreated A549 cells stimulated with EGF (100ng/ml) for generation of focal adhesions (stained for Vinculin, green) and stress fibers (stained for phalloidin, red). JWH-015 and Win55,212-2 inhibit formation of focal adhesions and stress fibers in NSCLC cells.