Fig. 3.
Effect of CZP on productivity in the workplace in the RAPID 1 (Week 52) and RAPID 2 (Week 24) trials [26]. Results are shown at baseline and study end. (A) Work days missed (absenteeism) due to arthritis per month. (B) Days with work productivity reduced by ≥50% (presenteeism) due to arthritis per month. (C) RA interference with work productivity per month (0–10 scale, 0 = no interference, 10 = complete interference). The analysis population in RAPID 1 and 2 trials was the intention-to-treat population (employed patients only). *P ≤ 0.05 vs placebo plus MTX. Analyses were performed using a non-parametric bootstrap t-test and the last observation carried forward approach. Adapted from Kavanaugh et al. [26] with permission of John Wiley & Sons Inc.