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. Author manuscript; available in PMC: 2011 Oct 15.
Published in final edited form as: Cancer Res. 2010 Sep 2;70(20):8108–8116. doi: 10.1158/0008-5472.CAN-10-2579

Figure 5. The effect of miR-21 on potential apoptotic effectors.

Figure 5

(A and B) PC3 cells transduced with control vector and PC3 cells overexpressing miR-21 (+miR-21) were treated with IFN (1000 IU/ml) for the indicated times, and cell lysates were immunoblotted for total and phosphorylated Akt levels (A) or p85 and actin (B). (C) DU145 cells transduced with anti-miR control (EV) and DU145 cells in which miR-21 was knocked down (Anti-miR-21) were immunoblotted for the indicated proteins. For analysis of STAT3 phosphorylation cells were treated with IFN (1000 IU/ml, 2 hr)