Skip to main content
. Author manuscript; available in PMC: 2010 Dec 28.
Published in final edited form as: Ann Intern Med. 2010 Mar 16;152(6):380–390. doi: 10.1059/0003-4819-152-6-201003160-00008

Appendix Table 3.

Potential Predictors of the Cumulative Relative Hazards for Short-Term (1-Year) All-Cause Mortality, Exploring Heterogeneity by Using Categorical and Meta-regression Analyses*

Variable Women Men
All Studies Outlying Study Omitted† All Studies Outlying Study Omitted†
R2, % P Value R2, % P Value R2, % P Value R2, % P Value
Categorical meta-analyses
 Region‡ <0.001 0.64 <0.001 0.19
 Hip fracture population source 0.23 0.134 0.96 0.27
 Patients with hip fracture considered for inclusion 0.24 0.32 0.38 0.48
 Control population source 0.28 0.44 0.083 0.072
 Procedure to ascertain death 0.27 0.43 0.58 0.71
Meta-regression analyses
 Latitude 0.2 0.84 2.4 0.57 1.7 0.48 2.4 0.48
 Starting year of study 0.2 0.85 0.3 0.83 5.0 0.21 0.1 0.88
 Duration of study, y§ 21.6 0.047 8.7 0.28 23.9 0.008 10.1 0.154
 Included participants with hip fracture, n 2.2 0.49 4.9 0.35 0.9 0.65 0.1 0.93
 Average age at hip fracture, y 9.3 0.18 12.1 0.177 0.2 0.82 0.2 0.84
 Underlying risk∥ 15.4 0.043 22.2 0.030 6.5 0.174 2.7 0.45
*

Between-group heterogeneity P value for categorical meta-analyses and model P value for meta-regression analyses. P values are presented without adjustment for multiple testing.

†

The outlying study is the Dubbo Osteoporosis Epidemiology Study, which was done in Australia and had a 15-year observation period (66). The authors acknowledge that there was probably selection bias in their study because participants were healthier than nonparticipants (67).