Figure 5.
Quantitation of cellular infiltrates in the spinal cords of wild-type and Bcl-xL transgenic mice. The cords were collected on day 13 after immunization and stained with markers for macrophages (Mac-1), T cells (TCR αβ), B cells (B220), class II MHC (MHC II), and IL-2R (CD25). The mean number of labeled cells per 100 mm2 of spinal cord tissue was calculated for each marker using the KS 400 image analysis system (Carl Zeiss). The x axis represents the number of cells per 100 mm2 of tissue. There were significant differences between the 2 groups in all the markers listed (AP < 0.0001, BP = 0.0004, CP = 0.0028 for B220 by t test).