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. 2010 Sep 21;19(24):4759–4773. doi: 10.1093/hmg/ddq402

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© The Author 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Significantly reduced spontaneous Ca²⁺ signalling activity in the developing cochlea of Cx30^T5M/T5M mice. Pooled data obtained by recording spontaneous Ca²⁺ transients for 7 min in each of n = 4 cultures from four different mice of each genotype (Cx30^+/+, Cx30^+/T5M, Cx30^T5M/T5M). (A) Waveforms of spontaneous Ca²⁺ transients versus time; solid lines are spline interpolations through average data (symbols) and dashed lines mark 95% confidence intervals. (B) Probability histograms of Ca²⁺ transient peak amplitude. Error bars represent s.d.; solid lines are peak amplitude cumulative probability. (C) Box-and-whisker diagrams for data in (B). For symbolism, see http://en.wikipedia.org/wiki/File:Boxplot_vs_PDF.png. P < 3 × 10^–6 indicates the probability that the means of Cx30^+/+ and Cx30^T5M/T5M data are equal based on one-way ANOVA. (D) Scatter plots of area invaded by Ca²⁺ transients versus peak amplitude.