Figure 7.
Reduction of asthmatic response. Bronchoalveolar lavage fluid eosinophils, monocytes, macrophages, and lymphocytes (a) and airway edema (b) were determined in controls (Saline) and OVA-treated mice in the absence (OVA) or presence (Ref-1 inhibitor/OVA) of PNRI-299. *, P < 0.05 vs. OVA by Student's two-tailed t test. (c) RT-PCR assay of IL-4, IL-5, IL-13, eotaxin, and CCR3 pulmonary gene expression.
