. Author manuscript; available in PMC: 2011 Nov 1.

Published in final edited form as: Pharmacogenet Genomics. 2010 Nov;20(11):687–699. doi: 10.1097/FPC.0b013e32833fe789

Table 2.

Nonsynonymous variants of OCT3 (SLC22A3) identified in three populations in the 1000 Genomes Project

dbSNP ID numbers	Genomic position	Amino Acid position	CDS position	Nucleotide change	Amino Acid change	CEU Freqency (n=57)	CHB /JPT Freqency (n=59)	YRI Freqency (n=56)
rs8187717	160689787	116	346	G > T	Ala >Ser	0	0	0.054
N/A	160748087	186	558	G > A	Leu >Phe	0	0.076	0.045
N/A	160778107	388	1162	G > T	Val >Met	0.009	0	0
N/A	160778212	423	1267	G > T	Val >Phe	0	0.068	0

ID numbers in bold indicate non-synonymous variants which were studied in this investigation. CEU, Caucasians in Utah; CHB/JPT, Chinese in Beijing and Japanese in Tokyo; YRI, Yoruba in Ibadan in Nigeria; n = number of chromosomes examined;