TABLE 4.
Protective effect of C*1601 appears to be caused by LD with B*4403
| DR | HLA-B | HLA-C | Not trans | Trans | Trans proportion (%) | P |
|---|---|---|---|---|---|---|
| All | B*4403 | All | 282 | 118 | 29.50 | |
| All | B*4403 | C*1601 | 156 | 66 | 29.73 | |
| All | B*4403 | not C*1601 | 115 | 40 | 25.81 | NS |
| All | All | C*1601 | 173 | 80 | 31.62 | |
| All | B*4403 | C*1601 | 156 | 66 | 29.73 | |
| All | not B*4403 | C*1601 | 17 | 14 | 45.16 | <0.13 |
| DR7† | B*4403 | not C*1601 | 81 | 10 | 10.99 | |
| DR7 | not B*4403 | C*1601 | 3 | 4 | 57.14 | <0.0074 |
| DR7 | B*4403 | C*1601 | 124 | 36 | 22.50 | |
| DR7 | B*4403 | not C*1601 | 81 | 10 | 10.99 | <0.023 |
| DR7 | B*4403 | C*1601 | 124 | 36 | 22.50 | |
| DR7 | not B*4403 | C*1601 | 3 | 4 | 57.14 | <0.036 |
†DRB1*0701 DQB1*0201.