Fig. 7.
iNOS inhibitors prevented EtOH-induced increases in alanine aminotransferase (ALT). Chronic EtOH consumption by rats significantly increased serum ALT levels, an index of liver cell injury. iNOS inhibitors significantly inhibited EtOH-induced increases in ALT: back to 91+15 U/dl by L-NIL and 96+16 U/dl by L-NAME. Data are expressed as mean ± S.E. for N=6 rats for each group. Differences between groups were analyzed using ANOVA, *: p<0.05 compared to dextrose-fed rats (controls),, #: p<0.05 compared to alcohol-fed rats (10 weeks).
