Table 1. Patient characteristics.

Characteristic	No. (%) or Median (range)
Number of patients	140
Age, years	68 (44–93)
PSA, ng/mL	50 (2–2159)
Treatment of the primary tumour
Surgery	42 (30%)
Radiation	37 (26%)
No primary therapy	61 (44%)
Prior hormone therapy	140 (100%)
1 line	32 (23%)
2 lines	42 (30%)
3 lines	37 (25%)
≥ 4 lines	29 (21%)
Ketoconazole	63 (45%)
Prior chemotherapy
None	65
Any	75
1 line	50
2 or more lines	25
Chemotherapy-Naive CTCs (n=60)
<5	44
≥5	16
Post-chemotherapy CTCs (n=68)
<5	33
≥5	35

Sites of disease	Total	Evaluable by PCWG2
Bone disease	109	109^a
Bone only	41	41^a
Bone and soft tissue:	68	68^a
Soft tissue disease	92	59^b
Lymph node only	21	17^b
Lymph node and bone	54	31^b
Visceral and bone	12	8^b
Visceral only	1	1^b
Other (pelvis/bladder) and bone	2	q^b
Other (pelvis/bladder) alone	2	0^b
No evidence of metastases	7	N/A

Number with bone disease evaluable by PCWG2

Number with soft tissue disease evaluable by PCWG2