. 2010 Jul 22;285(40):31055–31065. doi: 10.1074/jbc.M109.079962

TABLE 2.

Effect of Foxo1 miRNA on developing tibia

Bone volume fraction (BVF), bone mineral density (BMD), and total mineral content (Min Cont) were determined by microCT. Expression of Foxo1 (Foxo 1 exp), Foxo3 (Foxo 3 exp), and Foxo4 (Foxo 4 exp) measured by semiquantitative RT-PCR in tibiae infected with Foxo1 miRNA viral vector is presented relative to levels in tibiae infected with control miRNA vector. Data are expressed as means ± S.D. of three experiments.

	Control	Foxo 1 miRNA
Foxo 1 exp	1	0.32 ± 0.06^a
Foxo 3 exp	1	1.2 ± 0.24
Foxo 4 exp	1	1.3 ± 0.26
BVF (%)	13.7 ± 1.87	8.54 ± 0.94^a
BMD (mg/cc)	263.1 ± 18.27	232.3 ± 15.54^a
Min Cont (μg)	5.6 ± 1.4	2.3 ± 0.8^a

^a Significantly different from control miRNA values (p < 0.05).