TABLE 3.
Detection of JCV large T Ag and capsid protein VP1 in brain, kidney, bone, spleen, and lymph node FFPE samples from HIV-positive PML, HIV-positive, and HIV-negative individuals
| Sample type | Group | No. positive/total no. of samples tested (%)a |
||
|---|---|---|---|---|
| Large T Ag | Capsid protein VP1 | T Ag or VP1 | ||
| Brain | HIV positive/PML | 21/24 (88) | 20/24 (83) | 23/24 (96) |
| HIV positive | 1/18 (6) | 0/18 | 1/18 (6) | |
| HIV negative | 1/19 (5) | 0/19 | 1/19 (5) | |
| Kidney | HIV positive/PML | 1/11 (9) | 0/11 | 1/11 (9) |
| HIV positive | 3/11 (27) | 0/11 | 3/11 (27) | |
| HIV negative | 0/12 | 0/12 | 0/12 | |
| Bone | HIV positive/PML | 1/13 (8) | 1/13 (8) | 2/13 (15) |
| HIV positive | 0/11 | 0/11 | 0/11 | |
| HIV negative | 0/12 | 0/12 | 0/12 | |
| Spleen | HIV positive/PML | 0/9 | 0/9 | 0/9 |
| HIV positive | 0/9 | 0/9 | 0/9 | |
| HIV negative | 0/9 | 0/9 | 0/9 | |
| Lymph node | HIV positive/PML | NA | NA | NA |
| HIV positive | 0/7 | 0/7 | 0/7 | |
| HIV negative | NA | NA | NA | |
a
NA, not available.